Assisted Hatching at Vita Altera Cyprus IVF Center
At Vita Altera Cyprus IVF Center, our mission is to make cutting-edge fertility innovations accessible and highly effective. One of the specialized techniques we offer is assisted hatching, a procedure designed to help embryos implant more easily in the uterine lining. While assisted hatching may not be essential for every IVF patient, numerous clinical studies and patient experiences—particularly among those in the UK—highlight its potential to boost pregnancy outcomes under specific conditions. Below, we provide a detailed overview of assisted hatching, the science behind it, and the reasons patients choose Vita Altera for this advanced reproductive method.
What Is Assisted Hatching?
Assisted hatching is a laboratory procedure carried out in conjunction with in vitro fertilization (IVF). In natural conception, a developing embryo must break through its protective outer shell (the zona pellucida) before attaching to the uterus. However, in some cases—especially in older patients or those with a history of failed implantations—this shell may be more rigid or thicker than average, complicating the embryo’s ability to “hatch.”
By gently thinning or creating a small opening in this shell, assisted hatching can make it easier for the embryo to emerge and embed into the uterine lining. The technique usually involves:
- Micromanipulation: Using high-powered microscopes to localize a specific spot on the zona pellucida.
- Precise Technique: A specialized laser or chemical solution is applied to make a minute breach in the shell.
- Safeguarding Embryo Health: The procedure is meticulously controlled to avoid damaging the underlying cells, allowing the embryo to continue developing in optimal conditions.
Who May Benefit from Assisted Hatching?
Women of Advanced Maternal Age
- Research shows that, in the UK, more women are delaying pregnancy into their late 30s and early 40s. As maternal age increases, the embryo’s zona pellucida can become denser, reducing the likelihood of successful implantation.
Repeated IVF Failures
- For those who have undergone multiple unsuccessful IVF cycles despite transferring seemingly healthy embryos, assisted hatching may offer a new avenue of hope. By facilitating embryo release from the shell, it can improve clinical pregnancy rates.
Elevated FSH Levels or Diminished Ovarian Reserve
- Patients displaying signs of diminished ovarian reserve (often evidenced by elevated FSH or low AMH) may have embryos with thicker zona pellucidas. Assisted hatching helps compensate for these challenges, potentially raising success rates.
Embryos with Excessively Thick Zona Pellucida
- In some cases, embryologists measure the thickness of the zona pellucida directly under the microscope. If it exceeds standard thresholds, assisted hatching may be recommended to aid hatching.
Science Behind Assisted Hatching
Zona Pellucida Dynamics
The zona pellucida’s role is to protect the embryo during early development and transit through the fallopian tubes. However, once the blastocyst stage is reached (Day 5 or 6 of embryo development), the embryo needs to break through this shell to adhere to the uterine wall.Laser vs. Chemical Methods
- Laser-Assisted: A highly focused laser beam thins or penetrates the zona pellucida at a precise location, typically using time-lapse imaging or advanced optical guidance. This approach offers enhanced consistency and lower risk of unintentional harm to embryonic cells.
- Chemical (Acid Tyrode’s) Method: A mild acid solution is used to dissolve a small hole in the zona pellucida. Strict control of application time is required to avoid potential cellular injury.
Clinical Validation
Studies indicate that assisted hatching may improve implantation rates in select patient groups. In the UK, fertility clinics often integrate data from systematic reviews and meta-analyses to determine whether assisted hatching can yield measurable benefits in clinical outcomes, particularly for older patients or those with recurrent IVF failure.Patient Information Confidentiality
Our first priority in all treatment procedures performed at Vita Altera Cyprus IVF Center is patient confidentiality.
Always Contact
Our patients can contact us at any time during the Assisted Hatching Techniques and ask any questions they may have.
Correct Treatment
Our patients only receive the Assisted Hatching Techniques they need. This way, they never lose any unnecessary time or money.
Assisted Hatching at Vita Altera: Our Approach
Personalized Consultation
- We begin by reviewing your entire fertility profile—age, ovarian reserve, previous IVF attempts, and embryo quality. Our recommendation for assisted hatching depends on careful evaluation, aiming to ensure you undergo only the procedures that genuinely enhance your likelihood of pregnancy.
State-of-the-Art Equipment
- Our embryology lab is equipped with advanced laser systems for pinpoint accuracy. Our specialized devices allow embryologists to perform the procedure with unmatched precision and minimal disturbance to the embryo.
Expert Embryology Team
- Embryologists at Vita Altera undergo rigorous training in micromanipulation techniques, ensuring the opening in the zona pellucida is optimally placed and sized.
Seamless Integration with Other Services
- In addition to assisted hatching, we offer comprehensive fertility care, including Cyprus Ivf Center collaborations, preimplantation genetic testing (PGT), vitrification of embryos, and more. This integrated approach allows us to tailor your treatment and increase your chances of a successful outcome.
Patient-Centered Experience
- We understand that traveling from the UK involves additional logistics—from scheduling flights to coordinating local accommodations. Our international patient department provides end-to-end support, enabling you to focus on your treatment and well-being.
The Assisted Hatching Process in Context of IVF
Ovarian Stimulation & Egg Retrieval
- As in conventional IVF, patients receive hormonal stimulation. Mature eggs are then collected under ultrasound guidance, usually with mild sedation.
Fertilization & Embryo Culture
- Sperm (from a partner or donor) is used to fertilize the eggs in our lab. Resulting embryos are cultured in specialized incubators that maintain stable temperature, gas composition, and humidity.
Assessment for Assisted Hatching
- Prior to embryo transfer—often on Day 3 or Day 5—our embryologists assess each embryo’s zona pellucida thickness and developmental stage. They decide whether assisted hatching is beneficial based on standardized clinical criteria.
The Micromanipulation Procedure
- Using a high-precision laser or chemical agent, a tiny aperture is created in the zona pellucida. Our embryologists must ensure minimal disruption to embryonic cells while providing an opening for potential “hatching.”
Embryo Transfer & Post-Procedure
- The embryo is placed into a thin catheter and transferred into the uterus under ultrasound guidance. After a brief rest, you can typically resume daily activities or plan your return trip to the UK.
Follow-Up & Pregnancy Test
- About 10–14 days post-transfer, a beta-hCG blood test verifies the success of implantation. Vita Altera’s clinical staff remains available for further queries and to advise on early pregnancy care.
Addressing Common Questions
Should You Consider Assisted Hatching?
Not every IVF cycle requires assisted hatching, but it can be a critical component for patients with specific challenges. If you have experienced multiple failed transfers, suspect diminished embryo quality, or are over 37–38 years of age, we encourage you to explore whether assisted hatching could raise your chances of success.
Begin Your Journey at Vita Altera Cyprus IVF Center
At Vita Altera Cyprus IVF Center, we combine scientific rigor with compassionate, personalized care. Whether you’re seeking advanced micromanipulation like assisted hatching or simply wish to learn more about your reproductive options, our dedicated team is here to support you every step of the way.
Reach out today for tailored guidance, a detailed assessment of your fertility prospects, and a warm, professional treatment environment that accommodates UK patients with ease. Through the synergy of expertise, advanced technology, and unwavering commitment, we strive to make your journey to parenthood as fruitful as possible.
FAQ About Assisted Hatching
There are many questions about the techniques, we have selected frequently asked questions about this service. If you do not see your answer, please contact us.