ERA Test at Vita Altera Cyprus IVF Center
At Vita Altera Cyprus IVF Center, our mission is to optimize every aspect of your fertility journey. While high-quality eggs, sperm, and embryos are essential for successful in vitro fertilization (IVF), the uterine environment is equally critical—particularly the timing and conditions under which an embryo implants. That is why we offer the Endometrial Receptivity Analysis (ERA) test, an innovative diagnostic tool that evaluates whether the endometrium (uterine lining) is precisely ready to receive an embryo.
Understanding the ERA Test
The ERA test is a molecular genetic screening method that assesses the receptivity window of the endometrial tissue. Essentially, it pinpoints the exact day—or narrow “implantation window”—when the uterus is most capable of supporting embryo implantation.
Why ERA Matters
Synchronizing Endometrium and Embryo Development
- In certain cases, patients with seemingly healthy embryos still experience repeated implantation failure. Research, including data from leading fertility clinics in the UK, reveals that some uterine linings do not mature in perfect sync with embryo development.
- By determining the optimal transfer day, the ERA test helps bridge this timing gap and significantly increases the odds of pregnancy.
Beyond Structural Pathologies
- Standard assessments such as ultrasound or hysteroscopy may detect uterine fibroids, polyps, or adhesions. While addressing these issues is crucial, they do not reveal the nuanced cellular environment that fosters implantation.
- The ERA test dives deeper, looking at the gene expression patterns of endometrial cells to determine whether the environment is truly receptive.
Recurrent Unsuccessful Attempts
- Patients with multiple failed IVF cycles—even when top-quality embryos were transferred—often benefit from ERA insights. Understanding a shifted or shortened receptivity window can be the key to unlocking a successful pregnancy.
The ERA Test in Donor Treatments
When using donor eggs or donor sperm, the embryo typically boasts very high developmental potential. In these scenarios, the main determinant of pregnancy success often shifts to the uterine lining’s readiness. By accurately pinpointing the ideal transfer day, ERA enhances the success rate, especially for couples who have already endured several unsuccessful cycles.
Importance for UK Patients
In the United Kingdom, an estimated 1 in 7 couples experiences fertility challenges. As more individuals opt for assisted reproductive therapies, advanced diagnostics like ERA are becoming increasingly relevant. By identifying whether the endometrium is truly receptive, couples can avoid further emotional and financial strain from repeated failures and make the most of each embryo transfer opportunity.
Patient Information Confidentiality
Our first priority in all treatment procedures performed at Vita Altera Cyprus IVF Center is patient confidentiality.
Always Contact
Our patients can contact us at any time during the Era Test Techniques and ask any questions they may have.
Correct Treatment
Our patients only receive the Era Test Techniques they need. This way, they never lose any unnecessary time or money.
How Is the ERA Test Performed?
Preparation & Monitoring
- The ERA test typically requires a “mock” or practice cycle that mirrors a frozen embryo transfer (FET) protocol.
- Hormone therapy (estrogen and progesterone) is administered to mimic the conditions under which an actual embryo transfer would occur.
Endometrial Biopsy
- At a carefully scheduled time—often day 5 or 6 of progesterone exposure—a small sample of endometrial tissue is collected.
- The procedure is often performed in a controlled environment under mild sedation for comfort, ensuring minimal discomfort or disruption.
Advanced Molecular Analysis
- The biopsy is analyzed using next-generation sequencing methods to examine over 200 genes linked to endometrial receptivity.
- Results typically return within 3–4 weeks, revealing whether the tissue is “Receptive” or “Non-Receptive” at the sampled time.
Adjustments to the Transfer Timeline
- If the lining is receptive on the sampled day, the subsequent embryo transfer can follow the same schedule in a real IVF cycle.
- If the test indicates a “Non-Receptive” result, adjustments—such as adding or removing a day of progesterone—help align the embryo transfer with the patient’s unique window of receptivity.
Planning ERA with a Frozen Embryo Transfer
To maximize the ERA test’s value, fertility specialists usually advise linking it to a frozen embryo transfer (FET) cycle. This approach offers several advantages:
Cyprus Ivf Center Collaboration
We place a high priority on advanced laboratory capabilities and state-of-the-art techniques, often working in concert with Cyprus Ivf Center. Through this collaboration, patients benefit from a robust cryopreservation program and meticulously monitored laboratory processes. That means if you require embryo storage or repeated cycles, the infrastructure is already in place to support optimal results.
Who Should Consider the ERA Test?
- Couples With Unexplained Implantation Failures: If you’ve had multiple IVF cycles fail despite transferring top-quality embryos, ERA may uncover a shifted or atypical receptivity window.
- Donor Egg/Donor Sperm Patients: When embryo quality is presumed high, focusing on uterine receptivity can be the decisive factor for success.
- Suspected Luteal Phase Disorders: Patients with irregular cycles or hormone imbalances that disrupt normal endometrial development.
- Those Seeking Customized Treatment: Personalized medicine is the hallmark of contemporary IVF. ERA fits well with this philosophy, offering tailored timing rather than one-size-fits-all protocols.
What About ERA Test Costs?
The price of an ERA test can depend on factors such as:
- Number of Preparatory Visits
- Medication Protocol for the Mock Cycle
- Biopsy Procedure Requirements
- Additional Diagnostics
We maintain transparent pricing discussions from the outset. Our commitment is to present you with a clear cost overview so you can make informed decisions regarding your fertility journey.
Why Vita Altera Cyprus IVF Center?
Scientific Expertise & Personalized Care
- Our reproductive endocrinologists have deep experience in diagnosing complex fertility challenges. Tailoring solutions like ERA test scheduling is a key part of our comprehensive approach.
International Patient Support
- Traveling from the UK to Cyprus for fertility care can be daunting, but our dedicated team helps coordinate each step—from medical consultations to lodging, making the process seamless and stress-free.
Advanced Lab Resources
- Our laboratory is equipped with the latest technology, ensuring an environment conducive to precise genetic testing and embryo culture. This synergy between advanced diagnostics and robust laboratory practices elevates success rates.
Transparent Communication & Follow-Up
- From your initial consultation through to result interpretation and embryo transfer, we keep you informed. Our specialists explain each step, ensuring you understand why we recommend specific interventions like ERA.
Ready to Explore ERA Testing at Vita Altera?
If you suspect that endometrial receptivity might be a factor in your fertility journey—or if you’ve experienced repeated implantation failures—contact us to discuss whether ERA aligns with your unique circumstances. At Vita Altera Cyprus IVF Center, our priority is to empower you with every scientific and clinical advantage, guiding you toward a successful pregnancy in the most informed and personalized way possible.
FAQ About Era Test
There are many questions about the techniques, we have selected frequently asked questions about this service. If you do not see your answer, please contact us.